Jiahao Huang

Ph.D. Candidate in Chemical Biology @ MIT

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Dota2ForLife

I am a Ph.D. candidate in Chemical Biology at the Massachusetts Institute of Technology, working with Prof. Xiao Wang. My research focuses on AI for Science, spatial transcriptomics, biomedical imaging, and production-grade tooling for computational biology.

Previously, I worked as an Associate Computational Biologist at the Broad Institute of MIT and Harvard, where I developed analysis pipelines for spatial transcriptomics and contributed to creating spatial atlases of the mouse central nervous system.

My work spans developing end-to-end analysis toolkits for spatial transcriptomics (Starfinder), spatially resolved single-cell translatomics (RIBOmap), and integrative in-situ mapping of the brain (STARmap PLUS).

I am also interested in large language models, agentic systems, and data/figure automation.

Latest Posts

Jan 27, 2025 Welcome to My Blog

Selected Publications

  1. Spatially resolved in situ profiling of mRNA life cycle at transcriptome scale in intact cells and tissues

    Jingyi* Ren, Haowen* Zeng, Jiahao* Huang, and 3 more authors

    Nature Protocols, 2025

  2. Spatially resolved single-cell translatomics at molecular resolution

    Haowen* Zeng, Jiahao* Huang, Jingyi* Ren, and 3 more authors

    Science, 2023

  3. Integrative in situ mapping of single-cell transcriptional states and tissue histopathology in a mouse model of Alzheimer’s disease

    Haowen* Zeng, Jiahao* Huang, Hanqing* Zhou, and 8 more authors

    Nature Neuroscience, 2023

  4. Spatial atlas of the mouse central nervous system at molecular resolution

    Hailing Shi, Yichen He, Yichun Zhou, and 8 more authors

    Nature, 2023